BDBM50320706 5-Benzoyl-2-{3-[3-fluoro-5-(4-methoxytetrahydro-4H-4-pyranyl)phenoxy]propyl}-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrochloride::CHEMBL1164949

SMILES COC1(CCOCC1)c1cc(F)cc(OCCCN2CCc3c(C2)c2ccccc2n3C(=O)c2ccccc2)c1

InChI Key InChIKey=MUNZCAUQYSGNEH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50320706   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320706(5-Benzoyl-2-{3-[3-fluoro-5-(4-methoxytetrahydro-4H...)
Affinity DataIC50:  2.06E+5nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of 5-hydroxyeicosatetraenoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320706(5-Benzoyl-2-{3-[3-fluoro-5-(4-methoxytetrahydro-4H...)
Affinity DataIC50:  1.82E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320706(5-Benzoyl-2-{3-[3-fluoro-5-(4-methoxytetrahydro-4H...)
Affinity DataIC50:  1.02E+5nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320706(5-Benzoyl-2-{3-[3-fluoro-5-(4-methoxytetrahydro-4H...)
Affinity DataIC50:  9.29E+4nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of LTB4 production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed