BDBM50320711 2-{3-[3-Fluoro-5-(4-methoxytetrahydro-4H-4-pyranyl)phenoxy]propyl}-8-methoxy-5-(2,4,6-trichlorobenzoyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole hydrochloride::CHEMBL1163221

SMILES COc1ccc2n(C(=O)c3c(Cl)cc(Cl)cc3Cl)c3CCN(CCCOc4cc(F)cc(c4)C4(CCOCC4)OC)Cc3c2c1

InChI Key InChIKey=XWOYELIINGSKQG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50320711   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320711(2-{3-[3-Fluoro-5-(4-methoxytetrahydro-4H-4-pyranyl...)
Affinity DataIC50:  4.54E+4nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of LTB4 production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320711(2-{3-[3-Fluoro-5-(4-methoxytetrahydro-4H-4-pyranyl...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320711(2-{3-[3-Fluoro-5-(4-methoxytetrahydro-4H-4-pyranyl...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of 5-lipoxygenase in human whole blood assessed as inhibition of 5-hydroxyeicosatetraenoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50320711(2-{3-[3-Fluoro-5-(4-methoxytetrahydro-4H-4-pyranyl...)
Affinity DataIC50:  3.67E+4nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of 12-hydroxyheptadecatrienoic acid production by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed