BDBM50321382 2-(3-(4-chlorophenyl)-3-oxo-1-phenylpropylthio)acetic acid::2-(3-(4-chlorophenyl)-3-oxo-1-phenylpropylthio)aceticacid::CHEMBL550259::PS46

SMILES OC(=O)CSC(CC(=O)c1ccc(Cl)cc1)c1ccccc1

InChI Key InChIKey=GKJHKTABFYRMPR-UHFFFAOYSA-N

Data  1 Kd  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50321382   

TargetSerine/threonine-protein kinase PKH2 [1-944](Candida albicans SC5314)
Universit£Tsklinikum Frankfurt

LigandPNGBDBM50321382(2-(3-(4-chlorophenyl)-3-oxo-1-phenylpropylthio)ace...)
Affinity DataEC50:  8.50E+4nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen Assay (Perkin Elmer) was performed according to the manufacturer's protocol in 384-well microtiter plates. Incubations were performe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50321382(2-(3-(4-chlorophenyl)-3-oxo-1-phenylpropylthio)ace...)
Affinity DataEC50:  1.33E+5nMAssay Description:Displacement of PIFtide from His-tagged PDK1 by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50321382(2-(3-(4-chlorophenyl)-3-oxo-1-phenylpropylthio)ace...)
Affinity DataKd:  1.80E+4nMAssay Description:Binding affinity to PDK1 (unknown origin) by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50321382(2-(3-(4-chlorophenyl)-3-oxo-1-phenylpropylthio)ace...)
Affinity DataEC50:  1.33E+5nMAssay Description:Competitive binding affinity to GST-PDK1 (unknown origin) preincubated for 1 to 10 mins by surface plasmon resonance in presence of biotin-PIFtideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed