BDBM50321943 CHEMBL1172957::N-(4-Aminosulfonylphenyl)-2-morpholino-9H-purin-6-amine

SMILES NS(=O)(=O)c1ccc(Nc2nc(nc3nc[nH]c23)N2CCOCC2)cc1

InChI Key InChIKey=CMWKVPYIDPPPIC-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50321943   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321943(CHEMBL1172957 | N-(4-Aminosulfonylphenyl)-2-morpho...)
Affinity DataIC50:  20nMAssay Description:Inhibition cSRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321943(CHEMBL1172957 | N-(4-Aminosulfonylphenyl)-2-morpho...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition cMetMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321943(CHEMBL1172957 | N-(4-Aminosulfonylphenyl)-2-morpho...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition EphB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321943(CHEMBL1172957 | N-(4-Aminosulfonylphenyl)-2-morpho...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition EphA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321943(CHEMBL1172957 | N-(4-Aminosulfonylphenyl)-2-morpho...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition FGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321943(CHEMBL1172957 | N-(4-Aminosulfonylphenyl)-2-morpho...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321943(CHEMBL1172957 | N-(4-Aminosulfonylphenyl)-2-morpho...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition cABlMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321943(CHEMBL1172957 | N-(4-Aminosulfonylphenyl)-2-morpho...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321943(CHEMBL1172957 | N-(4-Aminosulfonylphenyl)-2-morpho...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321943(CHEMBL1172957 | N-(4-Aminosulfonylphenyl)-2-morpho...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition ErbB2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321943(CHEMBL1172957 | N-(4-Aminosulfonylphenyl)-2-morpho...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321943(CHEMBL1172957 | N-(4-Aminosulfonylphenyl)-2-morpho...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition kitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50321943(CHEMBL1172957 | N-(4-Aminosulfonylphenyl)-2-morpho...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed