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BDBM50321990 3-(3,4-Dibromophenyl)-5-p-tolyl-4,5-dihydro-1H-pyrazole-1-carbothioamide::CHEMBL1173262

SMILES: Cc1ccc(cc1)C1CC(=NN1C(N)=S)c1ccc(Br)c(Br)c1

InChI Key: InChIKey=BAGBEDITHGNDKC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50321990   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50321990
PNG
(3-(3,4-Dibromophenyl)-5-p-tolyl-4,5-dihydro-1H-pyr...)
Show SMILES Cc1ccc(cc1)C1CC(=NN1C(N)=S)c1ccc(Br)c(Br)c1
Show InChI InChI=1S/C17H15Br2N3S/c1-10-2-4-11(5-3-10)16-9-15(21-22(16)17(20)23)12-6-7-13(18)14(19)8-12/h2-8,16H,9H2,1H3,(H2,20,23)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 9.83E+3n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of histidine-tagged recombinant EGFR autophosphorylation expressed in Sf9 cells by solid-phase ELISA


Bioorg Med Chem 18: 4606-14 (2011)


Article DOI: 10.1016/j.bmc.2010.05.034
BindingDB Entry DOI: 10.7270/Q22R3SMJ
More data for this
Ligand-Target Pair