BDBM50322233 8-(Benzofuran-3-ylmethyl)-3-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)methyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one oxalate::CHEMBL1171630

SMILES FCCn1cc(CN2CN(c3ccccc3)C3(CCN(Cc4coc5ccccc45)CC3)C2=O)nn1

InChI Key InChIKey=WEABCZGCKKUPTB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50322233   

TargetD(3) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50322233(8-(Benzofuran-3-ylmethyl)-3-((1-(2-fluoroethyl)-1H...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [125I]ABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50322233(8-(Benzofuran-3-ylmethyl)-3-((1-(2-fluoroethyl)-1H...)
Affinity DataKi:  2nMAssay Description:Displacement of [125I]ABN from human dopamine D2 long receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Washington University

Curated by ChEMBL
LigandPNGBDBM50322233(8-(Benzofuran-3-ylmethyl)-3-((1-(2-fluoroethyl)-1H...)
Affinity DataKi:  802nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50322233(8-(Benzofuran-3-ylmethyl)-3-((1-(2-fluoroethyl)-1H...)
Affinity DataKi:  978nMAssay Description:Displacement of [125I]ABN from human dopamine D4 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed