BDBM50322887 3-(N-(4-cyanophenyl)methylsulfonamido)-N-((2S,3R)-4-((S)-1-(cyclohexylamino)-1-oxopropan-2-ylamino)-3-hydroxy-1-phenylbutan-2-yl)benzamide::CHEMBL1210348

SMILES C[C@H](NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cccc(c1)N(c1ccc(cc1)C#N)S(C)(=O)=O)C(=O)NC1CCCCC1

InChI Key InChIKey=OUJNBZOVRLESMB-JPBRBXQBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50322887   

TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322887(3-(N-(4-cyanophenyl)methylsulfonamido)-N-((2S,3R)-...)
Affinity DataIC50:  190nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322887(3-(N-(4-cyanophenyl)methylsulfonamido)-N-((2S,3R)-...)
Affinity DataIC50:  4.22E+3nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322887(3-(N-(4-cyanophenyl)methylsulfonamido)-N-((2S,3R)-...)
Affinity DataIC50:  5.15E+3nMAssay Description:Inhibition of Cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed