BDBM50322902 3-(N-benzylmethylsulfonamido)-N-((2S,3R)-4-((S)-1-(cyclohexylamino)-1-oxopropan-2-ylamino)-3-hydroxy-1-phenylbutan-2-yl)benzamide::CHEMBL1210333

SMILES C[C@H](NC[C@@H](O)[C@H](Cc1ccccc1)NC(=O)c1cccc(c1)N(Cc1ccccc1)S(C)(=O)=O)C(=O)NC1CCCCC1

InChI Key InChIKey=YLWBAAGWRILMKX-FWGANANOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50322902   

TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322902(3-(N-benzylmethylsulfonamido)-N-((2S,3R)-4-((S)-1-...)
Affinity DataIC50:  180nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322902(3-(N-benzylmethylsulfonamido)-N-((2S,3R)-4-((S)-1-...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50322902(3-(N-benzylmethylsulfonamido)-N-((2S,3R)-4-((S)-1-...)
Affinity DataIC50:  600nMAssay Description:Inhibition of Cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed