BDBM50323196 4'-methylamentoflavone::CHEMBL378188::bilobetin
SMILES COc1ccc(cc1-c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(O)cc1)-c1cc(O)c2c(cc(O)cc2=O)o1
InChI Key InChIKey=RLWJDMMKIGHAMT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50323196
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataKi: 8.04E+4nMAssay Description:Non-competitive inhibition of SARS coronavirus 3C-like protease by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human MMP2 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human MMP3 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Meiji Pharmaceutical University
Curated by ChEMBL
Meiji Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human amyloid beta (1 to 40) assessed as reduction in aggregation measured after 24 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of human Cathepsin KMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 7.23E+4nMAssay Description:Inhibition of SARS coronavirus 3C-like protease after 60 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of BACE1 after 60 mins by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of recombinant human MMP9 preincubated for 30 mins followed by McaPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 substrate addition measured by fluoresce...More data for this Ligand-Target Pair