BDBM50323793 CHEMBL1214399::N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide

SMILES CC(C)S(=O)(=O)N[C@H]1Cc2ccc(cc2C1)-c1ccc(F)nc1

InChI Key InChIKey=QXQSUBKWSHMXDP-INIZCTEOSA-N

Data  10 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50323793   

TargetGlutamate receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50323793(CHEMBL1214399 | N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2...)
Affinity DataEC50:  2.50E+3nMAssay Description:Inhibition of human recombinant GluR2More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50323793(CHEMBL1214399 | N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50323793(CHEMBL1214399 | N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP3A4 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50323793(CHEMBL1214399 | N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP3A4 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50323793(CHEMBL1214399 | N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2D6 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50323793(CHEMBL1214399 | N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP1A2 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50323793(CHEMBL1214399 | N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C19 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50323793(CHEMBL1214399 | N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C19 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50323793(CHEMBL1214399 | N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50323793(CHEMBL1214399 | N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP1A2 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50323793(CHEMBL1214399 | N-[(2S)-5-(6-Fluoro-3-pyridinyl)-2...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2D6 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed