BDBM50323868 (S)-1-((4R,7S,13R)-13-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carbonyl)-N-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide::CHEMBL1214025

SMILES CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(C)(C)SSC1(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=PVNAJCHBKOKIIB-BHXQQXLMSA-N

Data  3 KI  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50323868   

TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323868((S)-1-((4R,7S,13R)-13-((S)-2-amino-3-(4-hydroxyphe...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]substance P frome human NK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Rattus norvegicus (Rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323868((S)-1-((4R,7S,13R)-13-((S)-2-amino-3-(4-hydroxyphe...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]substance P frome rat NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323868((S)-1-((4R,7S,13R)-13-((S)-2-amino-3-(4-hydroxyphe...)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [3H]DPDPE from rat mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323868((S)-1-((4R,7S,13R)-13-((S)-2-amino-3-(4-hydroxyphe...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at rat mu opioid receptor expressed in mouse HN9.10 cells assessed as [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323868((S)-1-((4R,7S,13R)-13-((S)-2-amino-3-(4-hydroxyphe...)
Affinity DataIC50:  130nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-K receptor(Rattus norvegicus (Rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323868((S)-1-((4R,7S,13R)-13-((S)-2-amino-3-(4-hydroxyphe...)
Affinity DataIC50:  18nMAssay Description:Displacement of [3H]substance P frome rat NK2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323868((S)-1-((4R,7S,13R)-13-((S)-2-amino-3-(4-hydroxyphe...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human opioid delta receptor expressed in mouse HN9.10 cells assessed as [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323868((S)-1-((4R,7S,13R)-13-((S)-2-amino-3-(4-hydroxyphe...)
Affinity DataIC50:  4.17E+3nMAssay Description:Displacement of [3H]DPDPE from rat mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323868((S)-1-((4R,7S,13R)-13-((S)-2-amino-3-(4-hydroxyphe...)
Affinity DataIC50:  72nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50323868((S)-1-((4R,7S,13R)-13-((S)-2-amino-3-(4-hydroxyphe...)
Affinity DataIC50:  0.417nMAssay Description:Displacement of [3H]substance P frome human NK1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed