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BDBM50324876 4-Chloro-N-isopropyl-N-[3-(4-methyl-piperazin-1-yl)-phenyl]-benzenesulfonamide::CHEMBL1222293

SMILES: CC(C)N(c1cccc(c1)N1CCN(C)CC1)S(=O)(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=RNABKDJNIGKLPH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50324876   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))
BDBM50324876
PNG
(4-Chloro-N-isopropyl-N-[3-(4-methyl-piperazin-1-yl...)
Show SMILES CC(C)N(c1cccc(c1)N1CCN(C)CC1)S(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C20H26ClN3O2S/c1-16(2)24(27(25,26)20-9-7-17(21)8-10-20)19-6-4-5-18(15-19)23-13-11-22(3)12-14-23/h4-10,15-16H,11-14H2,1-3H3
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Similars

Article
PubMed
n/an/a 243n/an/an/an/an/an/a



Korea Research Institute of Chemical Technology

Curated by ChEMBL


Assay Description
Displacement of [3H]mesulergine from human 5HT2C expressed in CHOKI cells


Bioorg Med Chem Lett 20: 5221-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.06.150
BindingDB Entry DOI: 10.7270/Q27W6CCH
More data for this
Ligand-Target Pair