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BDBM50325889 CHEMBL1224535::N-(1-((6-(4-fluoro-2-methoxyphenyl)pyridin-2-yl)methyl)-1H-indol-6-yl)-3-hydroxy-2,2-dimethylpropanamide

SMILES: COc1cc(F)ccc1-c1cccc(Cn2ccc3ccc(NC(=O)C(C)(C)CO)cc23)n1

InChI Key: InChIKey=KVEBRGSWEKDCPX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50325889   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50325889
PNG
(CHEMBL1224535 | N-(1-((6-(4-fluoro-2-methoxyphenyl...)
Show SMILES COc1cc(F)ccc1-c1cccc(Cn2ccc3ccc(NC(=O)C(C)(C)CO)cc23)n1
Show InChI InChI=1S/C26H26FN3O3/c1-26(2,16-31)25(32)29-19-9-7-17-11-12-30(23(17)14-19)15-20-5-4-6-22(28-20)21-10-8-18(27)13-24(21)33-3/h4-14,31H,15-16H2,1-3H3,(H,29,32)
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Similars

Article
PubMed
n/an/a 45n/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]CC55940 human cannabinoid CB1 receptor expressed in CHO cells by luciferase reporter gene assay


Bioorg Med Chem Lett 20: 5449-53 (2010)


Article DOI: 10.1016/j.bmcl.2010.07.091
BindingDB Entry DOI: 10.7270/Q2SN0958
More data for this
Ligand-Target Pair