BDBM50327600 6-(3-(4-(8-fluoronaphthalen-1-yl)piperazin-1-yl)propoxy)-5-methylisoindolin-1-one::CHEMBL1257970

SMILES Cc1cc2CNC(=O)c2cc1OCCCN1CCN(CC1)c1cccc2cccc(F)c12

InChI Key InChIKey=HNWDHNRLIUTHEU-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327600   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327600(6-(3-(4-(8-fluoronaphthalen-1-yl)piperazin-1-yl)pr...)
Affinity DataKi:  1.44nMAssay Description:Binding affinity to human 5HT1A receptor expressed in HeLa cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327600(6-(3-(4-(8-fluoronaphthalen-1-yl)piperazin-1-yl)pr...)
Affinity DataKi:  16.6nMAssay Description:Displacement of [3H]-Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327600(6-(3-(4-(8-fluoronaphthalen-1-yl)piperazin-1-yl)pr...)
Affinity DataKi:  65.7nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50327600(6-(3-(4-(8-fluoronaphthalen-1-yl)piperazin-1-yl)pr...)
Affinity DataKi:  174nMAssay Description:Displacement of [3H]-citalopram from human serotonin transporter expressed in HEK 293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed