BDBM50328056 CHEMBL1230648::N-((2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-(1-(4-neopentylthiophen-2-yl)cyclopropylamino)butan-2-yl)acetamide::N-[(1S,2R)-1-(3,5-difluorobenzyl)-3-({1-[4-(2,2-dimethylpropyl)thiophen-2-yl]cyclopropyl}amino)-2-hydroxypropyl]acetamide

SMILES CC(=O)N[C@@H](Cc1cc(F)cc(F)c1)[C@H](O)CNC1(CC1)c1cc(CC(C)(C)C)cs1

InChI Key InChIKey=YEGCCSKZPHGALE-LEWJYISDSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50328056   

TargetCathepsin D(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328056(CHEMBL1230648 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  395nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50328056(CHEMBL1230648 | N-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  470nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair