BDBM50328816 6-(((3S,4S)-4-(2-(3-Fluorophenethylamino)ethoxy)pyrrolidin-3-yl)methyl)pyridin-2-amine::6-{[(3S,4S)-4-(2-{[2-(3-fluorophenyl)ethyl]amino}ethoxy)pyrrolidin-3-yl]methyl}pyridin-2-amine::CHEMBL1230381

SMILES Nc1cccc(C[C@H]2CNC[C@H]2OCCNCCc2cccc(F)c2)n1

InChI Key InChIKey=LRTPFJLYXDIXQR-QFBILLFUSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50328816   

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50328816(6-(((3S,4S)-4-(2-(3-Fluorophenethylamino)ethoxy)py...)
Affinity DataKi:  220nMAssay Description:Inhibition of rat nNOS expressed in Escherichia coli assessed as inhibition of nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50328816(6-(((3S,4S)-4-(2-(3-Fluorophenethylamino)ethoxy)py...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of human nNOS expressed in Escherichia coli assessed as inhibition of nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50328816(6-(((3S,4S)-4-(2-(3-Fluorophenethylamino)ethoxy)py...)
Affinity DataKi:  1.32E+4nMAssay Description:Inhibition of mouse iNOS expressed in Escherichia coli assessed as inhibition of nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50328816(6-(((3S,4S)-4-(2-(3-Fluorophenethylamino)ethoxy)py...)
Affinity DataKi:  5.90E+4nMAssay Description:Inhibition of bovine eNOS expressed in Escherichia coli assessed as inhibition of nitric oxide formation by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed