BDBM50329478 (S)-2-(2-Adamantan-1-yl-acetylamino)-N-{3-[4-(3-amino-propylamino)-butylamino]-propyl}-3-cyclohexyl-propionamide::CHEMBL1269127

SMILES NCCCNCCCCNCCCNC(=O)[C@H](CC1CCCCC1)NC(=O)CC12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=BSXAXDHXYFYFPY-BFBPZRSYSA-N

Data  2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329478   

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50329478((S)-2-(2-Adamantan-1-yl-acetylamino)-N-{3-[4-(3-am...)
Show SMILES NCCCNCCCCNCCCNC(=O)[C@H](CC1CCCCC1)NC(=O)CC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C31H57N5O2/c32-10-6-13-33-11-4-5-12-34-14-7-15-35-30(38)28(19-24-8-2-1-3-9-24)36-29(37)23-31-20-25-16-26(21-31)18-27(17-25)22-31/h24-28,33-34H,1-23,32H2,(H,35,38)(H,36,37)/t25?,26?,27?,28-,31?/m0/s1
Affinity DataIC50: 105nMAssay Description:Antagonist activity at GluR1 expressed in Xenopus laevis oocytes assessed as inhibition of glutamate-induced current at -60mV holding potential by tw...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50329478((S)-2-(2-Adamantan-1-yl-acetylamino)-N-{3-[4-(3-am...)
Show SMILES NCCCNCCCCNCCCNC(=O)[C@H](CC1CCCCC1)NC(=O)CC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C31H57N5O2/c32-10-6-13-33-11-4-5-12-34-14-7-15-35-30(38)28(19-24-8-2-1-3-9-24)36-29(37)23-31-20-25-16-26(21-31)18-27(17-25)22-31/h24-28,33-34H,1-23,32H2,(H,35,38)(H,36,37)/t25?,26?,27?,28-,31?/m0/s1
Affinity DataIC50: 794nMAssay Description:Antagonist activity at NR1-1a/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced current at -60mV ...More data for this Ligand-Target Pair