BDBM50329488 5-Isoxazoyl-Cha-Ile-(3-[aminomethyl]phenyl)-(4-[aminomethyl]-piperidin-1-yl)methanone::CHEMBL1269133

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccno1)C(=O)NCc1cccc(c1)C(=O)N1CCC(CN)CC1

InChI Key InChIKey=HXLQLJFWNKMGET-NVLPUFGLSA-N

Data  3 EC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50329488   

TargetProteinase-activated receptor 2(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329488(5-Isoxazoyl-Cha-Ile-(3-[aminomethyl]phenyl)-(4-[am...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccno1)C(=O)NCc1cccc(c1)C(=O)N1CCC(CN)CC1
Show InChI InChI=1S/C33H48N6O5/c1-3-22(2)29(38-30(40)27(19-23-8-5-4-6-9-23)37-31(41)28-12-15-36-44-28)32(42)35-21-25-10-7-11-26(18-25)33(43)39-16-13-24(20-34)14-17-39/h7,10-12,15,18,22-24,27,29H,3-6,8-9,13-14,16-17,19-21,34H2,1-2H3,(H,35,42)(H,37,41)(H,38,40)/t22-,27-,29-/m0/s1
Affinity DataEC50:  251nMAssay Description:Agonist activity at PAR2 receptor in human HT-29 cells assessed as induction of intracellular calcium releaseMore data for this Ligand-Target Pair
TargetProteinase-activated receptor 2(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329488(5-Isoxazoyl-Cha-Ile-(3-[aminomethyl]phenyl)-(4-[am...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccno1)C(=O)NCc1cccc(c1)C(=O)N1CCC(CN)CC1
Show InChI InChI=1S/C33H48N6O5/c1-3-22(2)29(38-30(40)27(19-23-8-5-4-6-9-23)37-31(41)28-12-15-36-44-28)32(42)35-21-25-10-7-11-26(18-25)33(43)39-16-13-24(20-34)14-17-39/h7,10-12,15,18,22-24,27,29H,3-6,8-9,13-14,16-17,19-21,34H2,1-2H3,(H,35,42)(H,37,41)(H,38,40)/t22-,27-,29-/m0/s1
Affinity DataEC50:  200nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of intracellular calcium release measured for 300 secs by Fluo-3 AM dye-b...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 2(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50329488(5-Isoxazoyl-Cha-Ile-(3-[aminomethyl]phenyl)-(4-[am...)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccno1)C(=O)NCc1cccc(c1)C(=O)N1CCC(CN)CC1
Show InChI InChI=1S/C33H48N6O5/c1-3-22(2)29(38-30(40)27(19-23-8-5-4-6-9-23)37-31(41)28-12-15-36-44-28)32(42)35-21-25-10-7-11-26(18-25)33(43)39-16-13-24(20-34)14-17-39/h7,10-12,15,18,22-24,27,29H,3-6,8-9,13-14,16-17,19-21,34H2,1-2H3,(H,35,42)(H,37,41)(H,38,40)/t22-,27-,29-/m0/s1
Affinity DataEC50:  200nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of intracellular calcium release measured for 300 secs by Fluo-3 AM dye-b...More data for this Ligand-Target Pair