BDBM50329784 (Z)-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylic Acid Ethylamide::CHEMBL1271472

SMILES CCNC(=O)c1ccc2C(C(=Nc3ccc(CN4CCCCC4)cc3)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=UVBZZXVKQPKWOZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50329784   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329784((Z)-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)...)
Affinity DataIC50:  24nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329784((Z)-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)...)
Affinity DataIC50:  789nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329784((Z)-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)...)
Affinity DataEC50:  75nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed