BDBM50329786 (Z)-3-(phenyl(4-(piperidin-1-ylmethyl)phenylamino)methylene)-6-(pyrrolidine-2-carbonyl)indolin-2-one::CHEMBL1271632

SMILES O=C(C1CCCN1)c1ccc2C(C(=Nc3ccc(CN4CCCCC4)cc3)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=WESFPJRWWPIRIG-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50329786   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329786((Z)-3-(phenyl(4-(piperidin-1-ylmethyl)phenylamino)...)
Affinity DataEC50:  696nMAssay Description:Inhibition of TGFbeta receptor in human HaCaT cells assessed as Smad phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50329786((Z)-3-(phenyl(4-(piperidin-1-ylmethyl)phenylamino)...)
Affinity DataIC50:  245nMAssay Description:Inhibition of TGFbeta receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed