BDBM503303 6-Amino-2-(4-amino-4-methyl- piperidin-1-yl)-5-(3-chloro-phenyl)- pyrimidine-4-carboxylic acid amide::US11033547, Compound 2::US11696916, Compound 2

SMILES CC1(N)CCN(CC1)c1nc(N)c(-c2cccc(Cl)c2)c(n1)C(N)=O

InChI Key InChIKey=TWIOBPIJJIJRNM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 503303   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Merck Patent

US Patent
LigandPNGBDBM503303(6-Amino-2-(4-amino-4-methyl- piperidin-1-yl)-5-(3-...)
Affinity DataIC50:  2.10E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM503303(6-Amino-2-(4-amino-4-methyl- piperidin-1-yl)-5-(3-...)
Affinity DataIC50:  2.10E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent