BDBM503305 6-Amino-2-(4-amino-4-methyl- piperidin-1-yl)-5-(3-fluoro-phenyl)- pyrimidine-4-carboxylic acid amide::US11033547, Compound 4::US11696916, Compound 4
SMILES CC1(N)CCN(CC1)c1nc(N)c(-c2cccc(F)c2)c(n1)C(N)=O
InChI Key InChIKey=ONKAWTQARQHIQO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 503305
Affinity DataIC50: 3.70E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair