BDBM50330860 CHEMBL1201356::METHYLERGONOVINE::Methylergometrine

SMILES CC[C@@H](CO)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34

InChI Key InChIKey=UNBRKDKAWYKMIV-QWQRMKEZSA-N

Data  10 KI  1 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50330860   

LigandPNGBDBM50330860(CHEMBL1201356 | METHYLERGONOVINE | Methylergometri...)
Affinity DataKi:  0.490nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50330860(CHEMBL1201356 | METHYLERGONOVINE | Methylergometri...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Guinea pig)
Syntex Discovery Research

Curated by PDSP Ki Database
LigandPNGBDBM50330860(CHEMBL1201356 | METHYLERGONOVINE | Methylergometri...)
Affinity DataKi:  11.0nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50330860(CHEMBL1201356 | METHYLERGONOVINE | Methylergometri...)
Affinity DataKi:  12.4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50330860(CHEMBL1201356 | METHYLERGONOVINE | Methylergometri...)
Affinity DataKi:  12.6nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50330860(CHEMBL1201356 | METHYLERGONOVINE | Methylergometri...)
Affinity DataKi:  30.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1F(Human)
University of Alberta

Curated by PDSP Ki Database
LigandPNGBDBM50330860(CHEMBL1201356 | METHYLERGONOVINE | Methylergometri...)
Affinity DataKi:  31nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Guinea pig)
Syntex Discovery Research

Curated by PDSP Ki Database
LigandPNGBDBM50330860(CHEMBL1201356 | METHYLERGONOVINE | Methylergometri...)
Affinity DataKi:  52.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1E(Human)
Synaptic Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50330860(CHEMBL1201356 | METHYLERGONOVINE | Methylergometri...)
Affinity DataKi:  89nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 1E(Human)
Synaptic Pharmaceutical

Curated by PDSP Ki Database
LigandPNGBDBM50330860(CHEMBL1201356 | METHYLERGONOVINE | Methylergometri...)
Affinity DataKi:  89.1nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMultidrug and toxin extrusion protein 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50330860(CHEMBL1201356 | METHYLERGONOVINE | Methylergometri...)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed