BDBM503319 2-(4-Amino-4-methyl-piperidin-1- yl)-6-chloro-5-(3-fluoro-phenyl)- pyrimidine-4-carboxylic acid amide::US11033547, Compound 19::US11696916, Compound 19

SMILES CC1(N)CCN(CC1)c1nc(Cl)c(-c2cccc(F)c2)c(n1)C(N)=O

InChI Key InChIKey=SAITWYGSDMTAQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 503319   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Merck Patent

US Patent
LigandPNGBDBM503319(2-(4-Amino-4-methyl-piperidin-1- yl)-6-chloro-5-(3...)
Affinity DataIC50:  8.70E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM503319(2-(4-Amino-4-methyl-piperidin-1- yl)-6-chloro-5-(3...)
Affinity DataIC50:  8.70E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent