BDBM50333241 CHEMBL254781::N-(4-chlorophenyl)-N'-(2,2,6,6-tetramethylpiperidin-4-yl)-oxalamide::N1-(4-chlorophenyl)-N2-(2,2,6,6-tetramethylpiperidin-4-yl)oxalamide
SMILES CC1(C)CC(CC(C)(C)N1)NC(=O)C(=O)Nc1ccc(Cl)cc1
InChI Key InChIKey=ZKXLQCIOURANAD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50333241
Affinity DataIC50: 610nMAssay Description:Inhibition of HIV-1 isolate YTA48P HIV-1 gp120More data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
Bryn Mawr College
Curated by ChEMBL
Bryn Mawr College
Curated by ChEMBL
Affinity DataIC50: 7.37E+4nMAssay Description:Inhibition of HIV1 YU2 gp120 binding to CD4 expressing Cf2Th-CD4/CCR5 cells assessed as inhibition of viral infection after 48 hrsMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1 group M subtyp...)
Bryn Mawr College
Curated by ChEMBL
Bryn Mawr College
Curated by ChEMBL
Affinity DataKd: 3.70E+3nMAssay Description:Binding affinity to HIV1 YU2 gp120 by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Binding affinity to HIV1 cYTA48P envelope glycoprotein gp120 infected in human TZM-b1 cells assessed as induction of conformational changes measured ...More data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:CD4 mimetic activity at gp120 in HIV-1 KP-5mvcR infected in human TZM-bl cells assessed as inhibition of viral entry by measuring reduction in RLU by...More data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of HIV1 KP-5mp1 gp120 interaction with CD4 human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Moscow State University
Curated by ChEMBL
Moscow State University
Curated by ChEMBL
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant HIV1 reverse transcriptase by colorimetric assayMore data for this Ligand-Target Pair
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Moscow State University
Curated by ChEMBL
Moscow State University
Curated by ChEMBL
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant HIV-1 reverse transcriptase incubated for 2 hrs by colorimetric assayMore data for this Ligand-Target Pair
TargetEnvelope glycoprotein gp160(Human immunodeficiency virus 1)
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of HIV1 KP-5mvcR gp120 interaction with CD4 in human TZM-bl cells assessed as decrease in viral entry by MTT assayMore data for this Ligand-Target Pair