BDBM503333 2-(7-Amino-3-oxa-9-aza- bicyclo[3.3.1]non-9-yl)-5-(2,3- dichlorophenyl)-6-methyl- pyrimidine-4-carboxylic acid amide::US11033547, Compound 33::US11696916, Compound 33

SMILES Cc1nc(nc(C(N)=O)c1-c1cccc(Cl)c1Cl)N1C2COCC1CC(N)C2

InChI Key InChIKey=IZIJKPWQUPMEEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 503333   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Merck Patent

US Patent
LigandPNGBDBM503333(2-(7-Amino-3-oxa-9-aza- bicyclo[3.3.1]non-9-yl)-5-...)
Affinity DataIC50:  2.40E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM503333(2-(7-Amino-3-oxa-9-aza- bicyclo[3.3.1]non-9-yl)-5-...)
Affinity DataIC50:  2.40E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent