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BDBM50334544 (S)-N-(4-(2-aminoethyl)-4,5-dihydro-1H-imidazol-2-yl)pyridin-3-amine dihydrobromide::CHEMBL1644494

SMILES: NCC[C@H]1CN=C(Nc2cccnc2)N1

InChI Key: InChIKey=CVWCWWMXURGMEP-VIFPVBQESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50334544   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Imidazoline I1


(RAT)
BDBM50334544
PNG
((S)-N-(4-(2-aminoethyl)-4,5-dihydro-1H-imidazol-2-...)
Show SMILES NCC[C@H]1CN=C(Nc2cccnc2)N1
Show InChI InChI=1S/C10H15N5/c11-4-3-9-7-13-10(15-9)14-8-2-1-5-12-6-8/h1-2,5-6,9H,3-4,7,11H2,(H2,13,14,15)/t9-/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Gdansk University of Technology

Curated by ChEMBL


Assay Description
Inhibition of Sprague-Dawley rat imidazoline I1 receptor


Bioorg Med Chem 19: 156-67 (2011)


Article DOI: 10.1016/j.bmc.2010.11.039
BindingDB Entry DOI: 10.7270/Q2GH9J79
More data for this
Ligand-Target Pair