BDBM50334731 CHEMBL1642851::[3-(Naphthalen-1-sulfonyl)-1H-indazol-5-yl]-piperidin-4-yl-amine HCl

SMILES O=S(=O)(c1n[nH]c2ccc(NC3CCNCC3)cc12)c1cccc2ccccc12

InChI Key InChIKey=PBZTVWPXUNSZDN-UHFFFAOYSA-N

Data  9 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50334731   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334731(CHEMBL1642851 | [3-(Naphthalen-1-sulfonyl)-1H-inda...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334731(CHEMBL1642851 | [3-(Naphthalen-1-sulfonyl)-1H-inda...)
Affinity DataKi:  675nMAssay Description:Binding affinity to 5-HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334731(CHEMBL1642851 | [3-(Naphthalen-1-sulfonyl)-1H-inda...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to 5-HT1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334731(CHEMBL1642851 | [3-(Naphthalen-1-sulfonyl)-1H-inda...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to 5-HT1D receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334731(CHEMBL1642851 | [3-(Naphthalen-1-sulfonyl)-1H-inda...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to 5-HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334731(CHEMBL1642851 | [3-(Naphthalen-1-sulfonyl)-1H-inda...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to 5-HT7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334731(CHEMBL1642851 | [3-(Naphthalen-1-sulfonyl)-1H-inda...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to adrenergic alpha2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334731(CHEMBL1642851 | [3-(Naphthalen-1-sulfonyl)-1H-inda...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334731(CHEMBL1642851 | [3-(Naphthalen-1-sulfonyl)-1H-inda...)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to 5-HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334731(CHEMBL1642851 | [3-(Naphthalen-1-sulfonyl)-1H-inda...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at cloned human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed