BDBM50334748 (S)-3-Methyl-N1-[3-(naphthalen-1-sulfonyl)-1H-indazol-5-yl]-butane-1,2-diamine HCl::CHEMBL1642850

SMILES CC(C)[C@H](N)CNc1ccc2[nH]nc(c2c1)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=NNLCUDVEWOVADM-LJQANCHMSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50334748   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334748((S)-3-Methyl-N1-[3-(naphthalen-1-sulfonyl)-1H-inda...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]-LSD from cloned human 5-HT6 receptor expressed in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50334748((S)-3-Methyl-N1-[3-(naphthalen-1-sulfonyl)-1H-inda...)
Affinity DataIC50:  103nMAssay Description:Antagonist activity at cloned human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced cyclic AMP formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed