BDBM503351 6-amino-2-[(3R,4R)-3- (aminomethyl)-4-phenylpyrrolidin- 1-yl]-5-(2,3- dichlorophenyl)pyrimidine-4- carboxamide::US11033547, Compound 51::US11696916, Compound 51
SMILES NC[C@@H]1CN(C[C@H]1c1ccccc1)c1nc(N)c(-c2cccc(Cl)c2Cl)c(n1)C(N)=O
InChI Key InChIKey=GHZBTMYEGMTEBD-HIFRSBDPSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 503351
Affinity DataIC50: 1.50E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair