BDBM503351 6-amino-2-[(3R,4R)-3- (aminomethyl)-4-phenylpyrrolidin- 1-yl]-5-(2,3- dichlorophenyl)pyrimidine-4- carboxamide::US11033547, Compound 51::US11696916, Compound 51

SMILES NC[C@@H]1CN(C[C@H]1c1ccccc1)c1nc(N)c(-c2cccc(Cl)c2Cl)c(n1)C(N)=O

InChI Key InChIKey=GHZBTMYEGMTEBD-HIFRSBDPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 503351   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Merck Patent

US Patent
LigandPNGBDBM503351(6-amino-2-[(3R,4R)-3- (aminomethyl)-4-phenylpyrrol...)
Affinity DataIC50:  1.50E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM503351(6-amino-2-[(3R,4R)-3- (aminomethyl)-4-phenylpyrrol...)
Affinity DataIC50:  1.50E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent