BDBM50335284 CHEMBL1651349::N-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)phenylcarbamoyl]-leucyl-methylazaalanine-nitrile

SMILES CC(C)C[C@H](NC(=O)Nc1ccc(cc1)-c1noc(C)n1)C(=O)N(C)N(C)C#N

InChI Key InChIKey=ARWSHTCIMVGBCQ-INIZCTEOSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50335284   

TargetCathepsin K(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50335284(CHEMBL1651349 | N-[4-(5-Methyl-1,2,4-oxadiazol-3-y...)
Affinity DataKi:  0.0450nMAssay Description:Inhibition of human recombinant cathepsin K after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50335284(CHEMBL1651349 | N-[4-(5-Methyl-1,2,4-oxadiazol-3-y...)
Affinity DataKi:  0.190nMAssay Description:Inhibition of human cathepsin S after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50335284(CHEMBL1651349 | N-[4-(5-Methyl-1,2,4-oxadiazol-3-y...)
Affinity DataKi:  2nMAssay Description:Inhibition of human recombinant cathepsin L after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50335284(CHEMBL1651349 | N-[4-(5-Methyl-1,2,4-oxadiazol-3-y...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed