BDBM50335384 CHEMBL1651636::N-Hexoxypentyl-L-ido-1-deoxynojirimycin

SMILES CCCCCCOCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@@H]1CO

InChI Key InChIKey=RCXJPSZNTHETPE-MWDXBVQZSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50335384   

TargetCeramide glucosyltransferase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50335384(CHEMBL1651636 | N-Hexoxypentyl-L-ido-1-deoxynojiri...)
Affinity DataIC50:  100nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50335384(CHEMBL1651636 | N-Hexoxypentyl-L-ido-1-deoxynojiri...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335384(CHEMBL1651636 | N-Hexoxypentyl-L-ido-1-deoxynojiri...)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibition of recombinant GBA1 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50335384(CHEMBL1651636 | N-Hexoxypentyl-L-ido-1-deoxynojiri...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of sucrase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335384(CHEMBL1651636 | N-Hexoxypentyl-L-ido-1-deoxynojiri...)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant GBA2 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50335384(CHEMBL1651636 | N-Hexoxypentyl-L-ido-1-deoxynojiri...)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of lactase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed