BDBM50335395 CHEMBL1651555::N-Heptyl-L-ido-1-deoxynojirimycin

SMILES CCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@@H]1CO

InChI Key InChIKey=MBQCNYZEYQQTEE-WUHRBBMRSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50335395   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335395(CHEMBL1651555 | N-Heptyl-L-ido-1-deoxynojirimycin)
Affinity DataIC50:  7.00E+5nMAssay Description:Inhibition of recombinant GBA1 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50335395(CHEMBL1651555 | N-Heptyl-L-ido-1-deoxynojirimycin)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335395(CHEMBL1651555 | N-Heptyl-L-ido-1-deoxynojirimycin)
Affinity DataIC50:  40nMAssay Description:Inhibition of recombinant GBA2 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50335395(CHEMBL1651555 | N-Heptyl-L-ido-1-deoxynojirimycin)
Affinity DataIC50:  2.00E+5nMAssay Description:Inhibition of lactase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50335395(CHEMBL1651555 | N-Heptyl-L-ido-1-deoxynojirimycin)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of sucrase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50335395(CHEMBL1651555 | N-Heptyl-L-ido-1-deoxynojirimycin)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed