BDBM50335398 CHEMBL1651551::N-Heptyl-1-deoxynojirimycin

SMILES CCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO

InChI Key InChIKey=MBQCNYZEYQQTEE-YVECIDJPSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50335398   

TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50335398(CHEMBL1651551 | N-Heptyl-1-deoxynojirimycin)
Affinity DataKi:  95nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50335398(CHEMBL1651551 | N-Heptyl-1-deoxynojirimycin)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Mus musculus (Mouse))
TBA

Curated by ChEMBL
LigandPNGBDBM50335398(CHEMBL1651551 | N-Heptyl-1-deoxynojirimycin)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50335398(CHEMBL1651551 | N-Heptyl-1-deoxynojirimycin)
Affinity DataIC50:  500nMAssay Description:Inhibition of sucrase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335398(CHEMBL1651551 | N-Heptyl-1-deoxynojirimycin)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant GBA2 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50335398(CHEMBL1651551 | N-Heptyl-1-deoxynojirimycin)
Affinity DataIC50:  1.85E+4nMAssay Description:Inhibition of recombinant GBA1 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50335398(CHEMBL1651551 | N-Heptyl-1-deoxynojirimycin)
Affinity DataIC50:  5.00E+5nMAssay Description:Inhibition of lactase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed