BDBM503354 6-amino-2-[3-(aminomethyl)-3- hydroxyazetidin-1-yl]-5-(2,3- dichlorophenyl)-pyrimidine-4- carboxamide::US11033547, Compound 54::US11696916, Compound 54

SMILES NCC1(O)CN(C1)c1nc(N)c(-c2cccc(Cl)c2Cl)c(n1)C(N)=O

InChI Key InChIKey=IXHRRMHBQMVAQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 503354   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Merck Patent

US Patent
LigandPNGBDBM503354(6-amino-2-[3-(aminomethyl)-3- hydroxyazetidin-1-yl...)
Affinity DataIC50:  7.70E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM503354(6-amino-2-[3-(aminomethyl)-3- hydroxyazetidin-1-yl...)
Affinity DataIC50:  7.70E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent