BDBM50335964 1-(1-nicotinoylpiperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea::CHEMBL1668937

SMILES FC(F)(F)Oc1ccc(NC(=O)NC2CCN(CC2)C(=O)c2cccnc2)cc1

InChI Key InChIKey=VZQKXLOSWIHURY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50335964   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Ar£Te Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335964(1-(1-nicotinoylpiperidin-4-yl)-3-(4-(trifluorometh...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Ar£Te Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335964(1-(1-nicotinoylpiperidin-4-yl)-3-(4-(trifluorometh...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed