BDBM50336261 4-(4-hydroxy-3-methoxybenzylidene)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione::CHEMBL428441

SMILES [#6]-[#8]-c1cc(\[#6]=[#6]\[#6](=O)-[#6](=[#6]/c2ccc(-[#8])c(-[#8]-[#6])c2)\[#6](=O)\[#6]=[#6]\c2ccc(-[#8])c(-[#8]-[#6])c2)ccc1-[#8]

InChI Key InChIKey=UBAXBJGMRVTJRB-LUZURFALSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50336261   

TargetLactoylglutathione lyase(Homo sapiens (Human))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50336261(4-(4-hydroxy-3-methoxybenzylidene)-1,7-bis(4-hydro...)
Affinity DataKi:  3.60E+3nMAssay Description:Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Manipal Academy Of Higher Education

Curated by ChEMBL
LigandPNGBDBM50336261(4-(4-hydroxy-3-methoxybenzylidene)-1,7-bis(4-hydro...)
Affinity DataIC50:  83nMAssay Description:Inhibition of Wild type ABL (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Manipal Academy Of Higher Education

Curated by ChEMBL
LigandPNGBDBM50336261(4-(4-hydroxy-3-methoxybenzylidene)-1,7-bis(4-hydro...)
Affinity DataIC50:  67nMAssay Description:Inhibition of ABL T315I mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Manipal Academy Of Higher Education

Curated by ChEMBL
LigandPNGBDBM50336261(4-(4-hydroxy-3-methoxybenzylidene)-1,7-bis(4-hydro...)
Affinity DataIC50:  185nMAssay Description:Inhibition of ABL Q252H mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Manipal Academy Of Higher Education

Curated by ChEMBL
LigandPNGBDBM50336261(4-(4-hydroxy-3-methoxybenzylidene)-1,7-bis(4-hydro...)
Affinity DataIC50:  80nMAssay Description:Inhibition of ABL Y253F mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed