BDBM503363 6-amino-2-{[(1R,2S)-2- aminocyclohexyl]amino}-5-(2,3- dichlorophenyl)-pyrimidine-4- carboxamide::US11033547, Compound 65::US11696916, Compound 65
SMILES N[C@H]1CCCC[C@H]1Nc1nc(N)c(c(n1)C(N)=O)-c1cccc(Cl)c1Cl
InChI Key InChIKey=HZYYDNYGLLCFHE-WDEREUQCSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 503363
Affinity DataIC50: 3.70E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair