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BDBM50336424 1-(4-chlorophenyl)-4-(3,4-dimethoxybenzylidene)-3-(trifluoromethyl)-1H-pyrazol-5(4H)-one::CHEMBL1668291

SMILES: COc1ccc(\C=C2\C(=O)N(N=C2C(F)(F)F)c2ccc(Cl)cc2)cc1OC

InChI Key: InChIKey=AMFQIALECOUHGP-NTEUORMPSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336424   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ERO1-like protein alpha


(Homo sapiens (Human))
BDBM50336424
PNG
(1-(4-chlorophenyl)-4-(3,4-dimethoxybenzylidene)-3-...)
Show SMILES COc1ccc(\C=C2\C(=O)N(N=C2C(F)(F)F)c2ccc(Cl)cc2)cc1OC
Show InChI InChI=1S/C19H14ClF3N2O3/c1-27-15-8-3-11(10-16(15)28-2)9-14-17(19(21,22)23)24-25(18(14)26)13-6-4-12(20)5-7-13/h3-10H,1-2H3/b14-9+
PDB
MMDB

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Similars

Article
PubMed
n/an/a 8.00E+3n/an/an/an/an/an/a



East China University of Science and Technology

Curated by ChEMBL


Assay Description
Inhibition of human Ero1-Lalpha


Bioorg Med Chem Lett 21: 1118-21 (2011)


Article DOI: 10.1016/j.bmcl.2010.12.129
BindingDB Entry DOI: 10.7270/Q2CC10ZR
More data for this
Ligand-Target Pair