BDBM50336875 CHEMBL1672324::N2'-methyl-2-morpholino-N6-(quinolin-3-yl)-4,5'-bipyrimidine-2',6-diamine

SMILES CNc1ncc(cn1)-c1cc(Nc2cnc3ccccc3c2)nc(n1)N1CCOCC1

InChI Key InChIKey=JIPRSFBAFUWPLO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50336875   

LigandPNGBDBM50336875(CHEMBL1672324 | N2'-methyl-2-morpholino-N6-(quinol...)
Affinity DataEC50:  110nMAssay Description:Inhibition of PI3Kalpha-mediated Akt phosphorylation at Ser473 in human A2780 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50336875(CHEMBL1672324 | N2'-methyl-2-morpholino-N6-(quinol...)
Affinity DataIC50:  7nMAssay Description:Inhibition of PI3Kalpha after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed