BDBM50337280 4-phenylamino benzoic acid::CHEMBL1682199::US9271961, 4

SMILES OC(=O)c1ccc(Nc2ccccc2)cc1

InChI Key InChIKey=DPAMLADQPZFXMD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50337280   

TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337280(4-phenylamino benzoic acid | CHEMBL1682199 | US927...)
Affinity DataIC50:  2.80E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337280(4-phenylamino benzoic acid | CHEMBL1682199 | US927...)
Affinity DataIC50:  3.00E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337280(4-phenylamino benzoic acid | CHEMBL1682199 | US927...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337280(4-phenylamino benzoic acid | CHEMBL1682199 | US927...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of AKR1C2 by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337280(4-phenylamino benzoic acid | CHEMBL1682199 | US927...)
Affinity DataIC50:  2.79E+3nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337280(4-phenylamino benzoic acid | CHEMBL1682199 | US927...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of AKR1C3 by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed