BDBM50337284 3-[N-(4-chlorophenyl)amino]benzoic acid::CHEMBL1682203::US9271961, 8

SMILES OC(=O)c1cccc(Nc2ccc(Cl)cc2)c1

InChI Key InChIKey=UPJCPFBYPSSQEM-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50337284   

TargetAldo-keto reductase family 1 member C4(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337284(3-[N-(4-chlorophenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50:  4.87E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337284(3-[N-(4-chlorophenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50:  130nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337284(3-[N-(4-chlorophenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50:  1.90E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337284(3-[N-(4-chlorophenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50:  3.02E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337284(3-[N-(4-chlorophenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337284(3-[N-(4-chlorophenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50:  1.91E+4nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337284(3-[N-(4-chlorophenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of AKR1C2 by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337284(3-[N-(4-chlorophenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50:  3.02E+4nMAssay Description:Inhibition of recombinant AKR1C1 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C4(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337284(3-[N-(4-chlorophenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50:  4.87E+4nMAssay Description:Inhibition of recombinant AKR1C4 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337284(3-[N-(4-chlorophenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50:  140nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337284(3-[N-(4-chlorophenyl)amino]benzoic acid | CHEMBL16...)
Affinity DataIC50:  130nMAssay Description:Inhibition of AKR1C3 by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed