BDBM50337285 3-[N-(4-bromophenyl)amino]benzoic acid::CHEMBL1682204::US9271961, 9

SMILES OC(=O)c1cccc(Nc2ccc(Br)cc2)c1

InChI Key InChIKey=QGRMQUFALFJLGQ-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50337285   

TargetAldo-keto reductase family 1 member C4(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50:  9.14E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of COX2 expressed in baculovirus infected SF-21 cells assessed as formation of PGH2 from PGG2 using arachidonic acid as substrate preincub...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50:  1.80E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50:  3.13E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50: >5.00E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50: >5.00E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50:  120nMAssay Description:Inhibition of AKR1C3 by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of AKR1C2 by fluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C1(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50:  3.13E+4nMAssay Description:Inhibition of recombinant AKR1C1 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50:  130nMAssay Description:Inhibition of recombinant AKR1C3 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50:  1.81E+4nMAssay Description:Inhibition of recombinant AKR1C2 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C4(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50:  9.14E+4nMAssay Description:Inhibition of recombinant AKR1C4 assessed as NADP+ dependent oxidation of S-tetralol by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B1(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant AKR1B1 assessed as NADP+ dependent reduction of DL-glyceraldehyde by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member B10(Homo sapiens (Human))
University Of Pennsylvania

US Patent
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant AKR1B10 assessed as NADP+ dependent reduction of DL-glyceraldehyde by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50337285(3-[N-(4-bromophenyl)amino]benzoic acid | CHEMBL168...)
Affinity DataIC50:  120nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In DepthDetails US Patent