BDBM50337367 4-(1H-indazol-5-yl)-2-methylthiazole::CHEMBL1682542

SMILES Cc1nc(cs1)-c1ccc2[nH]ncc2c1

InChI Key InChIKey=LYYSRRLDPCPRDC-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50337367   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337367(4-(1H-indazol-5-yl)-2-methylthiazole | CHEMBL16825...)
Affinity DataKi:  513nMAssay Description:Inhibition of Rock2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337367(4-(1H-indazol-5-yl)-2-methylthiazole | CHEMBL16825...)
Affinity DataKi:  2.86E+3nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337367(4-(1H-indazol-5-yl)-2-methylthiazole | CHEMBL16825...)
Affinity DataKi: >3.75E+3nMAssay Description:Inhibition of Pak4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337367(4-(1H-indazol-5-yl)-2-methylthiazole | CHEMBL16825...)
Affinity DataKi:  4.16E+3nMAssay Description:Inhibition of Pim1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337367(4-(1H-indazol-5-yl)-2-methylthiazole | CHEMBL16825...)
Affinity DataKi:  4.45E+3nMAssay Description:Inhibition of aurora 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337367(4-(1H-indazol-5-yl)-2-methylthiazole | CHEMBL16825...)
Affinity DataKi: >8.88E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed