BDBM50337374 CHEMBL1682549::N-benzyl-4-(1H-indazol-5-yl)-5-phenylthiazol-2-amine

SMILES C(Nc1nc(c(s1)-c1ccccc1)-c1ccc2[nH]ncc2c1)c1ccccc1

InChI Key InChIKey=YJSIMMVEIYLSHC-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50337374   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337374(CHEMBL1682549 | N-benzyl-4-(1H-indazol-5-yl)-5-phe...)
Affinity DataKi:  822nMAssay Description:Inhibition of Rock2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337374(CHEMBL1682549 | N-benzyl-4-(1H-indazol-5-yl)-5-phe...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337374(CHEMBL1682549 | N-benzyl-4-(1H-indazol-5-yl)-5-phe...)
Affinity DataKi: >3.75E+3nMAssay Description:Inhibition of Pak4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337374(CHEMBL1682549 | N-benzyl-4-(1H-indazol-5-yl)-5-phe...)
Affinity DataKi: >4.90E+3nMAssay Description:Inhibition of aurora 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337374(CHEMBL1682549 | N-benzyl-4-(1H-indazol-5-yl)-5-phe...)
Affinity DataKi: >8.75E+3nMAssay Description:Inhibition of Pim1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337374(CHEMBL1682549 | N-benzyl-4-(1H-indazol-5-yl)-5-phe...)
Affinity DataKi: >8.88E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed