BDBM503374 2-((3aR,6aR)-4-Amino-hexahydro- cyclopenta-[c]pyrrol-2-yl)-5-(2,3- dichloro-phenyl)-6-methyl- pyrimidine-4-carboxylic acid amide::US11033547, Compound 76::US11696916, Compound 76
SMILES Cc1nc(nc(C(N)=O)c1-c1cccc(Cl)c1Cl)N1C[C@@H]2CCC(N)[C@H]2C1
InChI Key InChIKey=RMQMWZYNKFDZCH-RJXBTYEGSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 503374
Affinity DataIC50: 1.00E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair