BDBM503375 2-((3aR,4S,6aS)-4-Amino- hexahydro-cyclopenta-[c]pyrrol-2- yl)-5-(2,3-dichloro-phenyl)-6- methyl-pyrimidine-4-carboxylic acid amide::US11033547, Compound 77::US11696916, Compound 77
SMILES Cc1nc(nc(C(N)=O)c1-c1cccc(Cl)c1Cl)N1C[C@H]2CC[C@H](N)[C@H]2C1
InChI Key InChIKey=RMQMWZYNKFDZCH-OSMZGAPFSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 503375
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair