BDBM50339322 (5S,7R)-N-benzhydryl-5-phenyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide::CHEMBL1688102

SMILES FC(F)(F)[C@H]1C[C@H](Nc2c(cnn12)C(=O)NC(c1ccccc1)c1ccccc1)c1ccccc1

InChI Key InChIKey=DSZIJTUXGRIYIN-XZOQPEGZSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50339322   

TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd

Curated by ChEMBL
LigandPNGBDBM50339322((5S,7R)-N-benzhydryl-5-phenyl-7-(trifluoromethyl)-...)
Show SMILES FC(F)(F)[C@H]1C[C@H](Nc2c(cnn12)C(=O)NC(c1ccccc1)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C27H23F3N4O/c28-27(29,30)23-16-22(18-10-4-1-5-11-18)32-25-21(17-31-34(23)25)26(35)33-24(19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15,17,22-24,32H,16H2,(H,33,35)/t22-,23+/m0/s1
Affinity DataIC50: 380nMAssay Description:Inhibition of CaSR expressed in CHO cells incubated with compound for 10 mins measured after 1 hr by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair