BDBM503401 (5P)-2-[(3aS,6aR)-3a- (aminomethyl)-octahydro- cyclopenta[c]pyrrol-2-yl]-6-amino-5- (2,3-dichlorophenyl)-pyrimidine-4- carboxamide::US11033547, Compound 104::US11033547, Compound 105::US11696916, Compound 105
SMILES NC[C@]12CCC[C@H]1CN(C2)c1nc(N)c(-c2cccc(Cl)c2Cl)c(n1)C(N)=O
InChI Key InChIKey=OYZALVSWJSKCSW-OVWNDWIMSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 503401
Affinity DataIC50: 120nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair