BDBM50340446 4-(4-(3-(1H-pyrazol-4-yl)pyrrolidine-1-carbonyl)-3,4-dihydroquinoxalin-1(2H)-yl)-N-cyclopropylbenzamide::CHEMBL1761867
SMILES O=C(NC1CC1)c1ccc(cc1)N1CCN(C(=O)N2CCC(C2)c2cn[nH]c2)c2ccccc12
InChI Key InChIKey=OSDMMAOYAANGHP-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50340446
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi-Aventis R&D
Curated by ChEMBL
Sanofi-Aventis R&D
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair